In Ladies with normal codeine metabolism (typical CYP2D6 action), the quantity of codeine secreted into human milk is minimal and dose-dependent. There isn't any information on the consequences from the codeine on milk manufacturing.five.3 Ultra-Rapid Metabolism of Codeine and also other Chance Elements for Life-Threatening Respiratory Depression i
Infertility Persistent use of opioids, for instance codeine, a ingredient of promethazine HCl and codeine phosphate oral Alternative, may perhaps trigger minimized fertility in women and males of reproductive likely.Breathing issues (respiratory despair) that may lead to Demise and opioid withdrawal can happen if You begin using or quit having othe
In the event the reaction to an opioid antagonist is suboptimal or only brief in mother nature, administer supplemental antagonist as directed because of the products’s prescribing information. The respiratory depressant results of promethazine usually are not reversed by opioid antagonists, such as naloxone.Check the label with your prescription